Tag Archive: absolute granulocyte count

ANC Calculator: Knowledge of Your ANC Count Can Save Your Life

Overview: ANC Calculator is used to measure the neutrophil count in white blood cells. Learn more about it in the article as well as use our onsite version and watch our example video on how it is calculated

A complete blood count offers detailed information including three cell types – platelets, red blood cells, and white blood cells. These cells are basically found in the bone marrow in few areas of the body such as the skull, ribs, sternum, backbone, and so on. Each type has a separate function and if the count decreases, it can be very harmful for the individual and often leads to failure of immune system. To prevent such circumstances, one must measure the blood counts via an ANC Calculator to know precisely what one’s absolute neutrophil count or ANC count is.

Blood Cells – Types and Characteristic
Before understanding what the ANC does, it is imperative to know what these blood cells are. As mentioned before there are three types;
• Red Blood Cells or RBC is what carries oxygen through the system. Containing hemoglobin, these cells are also responsible for removing waste items from the tissues of the body.
• White Blood Cells or WBC is what helps the body fight diseases and infections. For a strong immune system the WBC count should fall between 3.3 and 8.7 K/ul.
• Platelets are responsible for blood clotting. They help in stopping the blood flow after injury by clotting the blood.

White Blood Cells and Neutrophils
White Blood Cells can be further divided into five types which travel across the body destroying infection in the body – neutrophils, basophils, eosinophils, lymphocytes, and monocytes. The one which dominates is Neutrophils which makes up 56% of WBCs in the body and is responsible for attacking bacteria and other infection inside the body, making you strong and infection resistant. Neutrophils can be further divided into two types – polys which refer to fully-grown neutrophils and bands which refer to young polys.

To maintain a healthy body one must maintain the level of neutrophils in the body. Monitoring it is necessary and this is where ANC comes to rescue.

What is ANC?
ANC or absolute neutrophil count measures the total number of neutrophils in the blood. Also called the absolute granulocyte count or AGC, the calculator follows a simple formula where the total number of WBC is measured along with the polys and bands’ percentage. Once that is measured, the number of WBC is multiplied by the percentage.

Instances when the neutrophil count is low, the risk of disease increases and this condition is called neutropenia. Next time you notice that the ANC count is low, look for symptoms of neutropenia such as high fever (known as neutropenic fever), sweating, shaking chills, body pain, general tiredness, frequent urination, shortness of breath, redness of skin, and so on.

If you are neutropenic, you can take care by doing the following:
• Wash hands as frequently as possible
• Check your body temperature at least once a day. Take note of any fluctuations and notify your doctor immediately. Do not consume any medicine for the fever without medical consultation.

 

• Shower Daily. Use unscented lotion after bathing to avoid the skin from drying and cracking.

You can always fight a disease if you know that you suffer from it. This is where an ANC Calculator comes in handy. So, if you notice that you suffer from one or more symptoms of Neutropenia then consult a doctor to gauge the ANC count and ideally raise the neutrophil count in your blood.

Permanent link to this article: http://www.absoluteneutrophilcount.net/2012/07/14/anc-calculator-knowledge-anc-count-save-life/

Absolute Neutrophil Count: Know Thy Immunity

 

Absolute Neutrophil Count (ANC) determined through formulation or an anc calculator, is an approximation of the number of Neutrophil Granulocytes/Neutrophilsor infection-fighting white blood cells (WBC) in your blood. It is also called Absolute Granulocyte Count (AGC) and is the key indicator in judging an infection as well as Neutroponic Fever also called Febrile Neutropenia.

Neutrophil Granulocytes are the most affluent of the white blood cells in the human body and form the backbone of our immune system. They are present in the blood stream and are the primary line-of-defense when an inflammation occurs. This inflammation could be caused by a bacterial contamination, some cancer or an environmental factor. It is a rule-of-thumb that whenever an infection occurs, the Neutrophil Granulocytes are the first to respond. They are a brand of full developed white blood cells, which play a decisive role in fighting infection and disease in our body. Moreover, Neutrophil Granulocytes play an intrinsic role to break proteins and help the body to utilize these broken fragments, to be absorbed and employed by the body more effectively. They amount to 50-70 percent of the total infection fighting white blood cells and are formed in the bone marrow. Once configured, they penetrate the blood stream by compressing through the capillaries and target the inflammatory area.

Absolute Neutrophil Count is a more precise approximation of your risk of infection than your WBC alone. Your ANC can specify your requirement for explicit cure, such as   growth factors (also called granulocyte-colony stimulating factors or G-CSFs). If you are experiencing radiation or chemotherapy, it is your ANC count that is employed to gauge the condition of your immune system.

Analytical Importance

A customary Absolute Neutrophil Count is above 1,500 cells per microliter. An ANC less than 500 cells/µL is termed as Neutropenia. This considerably increases the risk of infection as well as Febrile Neutropenia or Neutropenic fever. Neutropenia is the condition of a low ANC; however “Neutrophilia” specifies an elevated count.

ANC Calculation:

The unit of ANC is cells per microliter (µL). A microliter is equivalent to one cubic millimeter of blood. The ANC is estimated from “measurements of the total number of white blood cells (WBC)”.

Absolute Neutrophil Count (ANC) Range:

Absolute Neutrophil Count (ANC) of 1000-1800: Majority of patients will require chemotherapy and the possibility of infection in minimal.

Mild Neutropenia-ANC of 500-1000: A temperate threat of disease or infection.

Severe Neutropenia-ANC of less than 500: Extreme risk of infection.

Absolute Neutrophil Count is an extremely important aspect of the human body. One must be conscious  of its values, self monitoring through anc calculator as it could easily determine the difference between life and death.

Permanent link to this article: http://www.absoluteneutrophilcount.net/2012/05/18/absolute-neutrophil-count-thy-immunity/